⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932651 | 0.71 | — | — | |
| SCHEMBL7794999 | 0.70 | — | — | |
| SCHEMBL4530603 | 0.67 | — | — | |
| SCHEMBL11206227 | 0.67 | MAPT (0.38) | — | |
| SCHEMBL20343542 | 0.67 | MAP3K14 (0.34) | — | |
| SCHEMBL11206098 | 0.67 | MAPT (0.38) | — | |
| SCHEMBL13977388 | 0.67 | MAPT (0.38) | — | |
| SCHEMBL11206101 | 0.67 | MAPT (0.38) | — | |
| SCHEMBL383250 | 0.67 | — | — | |
| SCHEMBL14750009 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559533-B1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0474243-B1 | 1-Methylcarbapenem derivatives and process for preparation thereof | TANABE SEIYAKU CO (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5589592-A | Process for preparing β-lactam derivative and synthetic intermediate | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| US-5414081-A | Treating a 1-aza-3-thiabicycloalkane with base and phosphine or phosphite desulfurizing agent, and reacting the product with an active esterifying agent | TANABE SEIYAKU CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0559533-A1 | Process for preparing beta-lactam derivative and synthetic intermediate thereof | TANABE SEIYAKU CO., LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |
| US-5208348-A | Intermediates for thienamycin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1993-05-04 | — | — | US | disclosed |
| US-5153187-A | Microbiocides having stability against dehydropeptidase and high absorrbability by oral administration | TANABE SEIYAKU CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0474243-A1 | 1-Methylcarbapenem derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-03-11 | — | — | EP | disclosed |