Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54807 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL29373703 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11088562 | 0.95 | ALDH1A1 (0.57) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10383232 | 0.94 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11088505 | 0.92 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10455416 | 0.92 | MAPT (0.46) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10382723 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10755688 | 0.91 | MAPT (0.50) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10854974 | 0.91 | ATM (0.45) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL10915090 | 0.90 | ALDH1A1 (0.51) | ALDH1A1KDM4ENPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0574418-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |