Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728126 | 0.86 | GAA (0.55) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL9037614 | 0.85 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| Trifloxysulfuron SCHEMBL64184 | 0.85 | GAA (0.55) | GAAMAPTTP53GLACDK1 | |
| Trifloxysulfuron SCHEMBL15449154 | 0.85 | GAA (0.55) | GAAMAPTTP53GLACDK1 | |
| Trifloxysulfuron SCHEMBL301007 | 0.84 | GAA (0.54) | GAAMAPTTP53GLACDK1 | |
| Trifloxysulfuron SCHEMBL14768215 | 0.83 | GAA (0.53) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11001284 | 0.83 | GAA (0.57) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL8882355 | 0.83 | GAA (0.54) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL9847509 | 0.83 | GAA (0.54) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL9522827 | 0.82 | GAA (0.58) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540697-B1 | SULFONYLUREAS | CIBA GEIGY AG (CH) | 1998-06-03 | — | — | EP | claimed |
| US-5403814-A | Preemergence and postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1995-04-04 | — | — | US | claimed |
| EP-0540697-A1 | NOVEL SULFONYLUREAS | Novartis AG (CH) | 1993-05-12 | — | — | EP | claimed |
| WO-1992016522-A1 | NOVEL SULFONYLUREAS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | claimed |
| EP-0540697-B1 | SULFONYLUREAS | CIBA GEIGY AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| US-5625071-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5403814-A | Preemergence and postemergence herbicides | CIBA-GEIGY CORPORATION (US) | 1995-04-04 | — | — | US | disclosed |
| EP-0540697-A1 | NOVEL SULFONYLUREAS | Novartis AG (CH) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992016522-A1 | NOVEL SULFONYLUREAS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | disclosed |