Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882355 | 0.89 | GAA (0.54) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9847509 | 0.86 | GAA (0.54) | GAACDK1MAPTTP53GLA | |
| SCHEMBL8535463 | 0.85 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9522827 | 0.85 | GAA (0.58) | GAACDK1MAPTTP53GLA | |
| Trifloxysulfuron SCHEMBL64184 | 0.85 | GAA (0.55) | GAACDK1MAPTTP53GLA | |
| SCHEMBL29176414 | 0.85 | GAA (0.58) | GAACDK1MAPTTP53GLA | |
| Trifloxysulfuron SCHEMBL15449154 | 0.85 | GAA (0.55) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11001284 | 0.84 | GAA (0.57) | GAACDK1MAPTTP53GLA | |
| SCHEMBL8883721 | 0.84 | GAA (0.57) | GAACDK1MAPTTP53GLA | |
| SCHEMBL8380195 | 0.84 | GAA (0.54) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273610-B1 | Herbicidal pyridinesulfonylureas | DU PONT (US) | 1996-09-11 | — | — | EP | claimed |
| US-5393733-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-28 | — | — | US | claimed |
| EP-0334896-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| WO-1989001937-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-09 | — | — | WO | claimed |
| EP-0273610-A1 | Herbicidal pyridinesulfonylureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-06 | — | — | EP | claimed |
| WO-1988004297-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-16 | — | — | WO | claimed |
| EP-0273610-B1 | Herbicidal pyridinesulfonylureas | DU PONT (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5512535-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| US-5393733-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5209770-A | Containing pyrimidine ring | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5102444-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0343050-A1 | 6-Phenyl-3-piperazinylalkyl 1H,3H-pyrimidinedione-2,4 derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989001937-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-09 | — | — | WO | disclosed |
| US-4774337-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0273610-A1 | Herbicidal pyridinesulfonylureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |