Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL539160 | 0.97 | CA2 (0.45) | CA2ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL3012658 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL7149948 | 0.92 | CA2 (0.45) | CA2 | |
| SCHEMBL246641 | 0.92 | — | — | |
| SCHEMBL30170704 | 0.90 | — | — | |
| SCHEMBL28755902 | 0.90 | — | — | |
| SCHEMBL28728454 | 0.90 | — | — | |
| Ether SCHEMBL3368640 | 0.85 | CA2 (0.43) | CA2ALDH1A1TSHR | |
| Dimethylamine SCHEMBL16895125 | 0.85 | CA2 (0.43) | CA2 | |
| Alcohol SCHEMBL28245603 | 0.84 | CA2 (0.62) | CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227313-A | Compatible low crystalline silica spacers | 哈利伯顿能源服务公司 | 2021-08-06 | — | — | CN | disclosed |
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-5728668-A | PRE-SPOTTING COMPOSITION | COLGATE PALMOLIVE COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0479923-A4 | LIQUID DETERGENTS AND CLEANING SOLUTIONS: BUILDER THEREFOR | — | 1992-11-25 | — | — | EP | disclosed |
| EP-0479923-A1 | LIQUID DETERGENTS AND CLEANING SOLUTIONS: BUILDER THEREFOR | PQ Corporation (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000330-A2 | LIQUID DETERGENTS AND CLEANING SOLUTIONS: BUILDER THEREFOR | PQ CORPORATION (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0373851-A2 | Detergent composition comprising betaine and ether sulphate | UNILEVER PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| US-3989534-A | CEMENTS, GUAR, BENTONITE, SURFACTANTS, PERLITE, VERMICULITE, SILICA SPHERES | PLUNGUIAN MARK | 1976-11-02 | — | — | US | disclosed |