Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 6/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535576 | 0.95 | TAOK3 (0.44) | MCHR1TAOK3TAOK1HTR2ANPC1 | |
| SCHEMBL8535363 | 0.86 | NPC1 (0.48) | TAOK3TAOK1NPC1LMNANFKB1 | |
| SCHEMBL8532626 | 0.83 | TAOK3 (0.44) | TAOK3TAOK1HTR2ASMN1; SMN2TP53 | |
| SCHEMBL8536472 | 0.83 | NPC1 (0.50) | MCHR1TAOK3NPC1LMNANFKB1 | |
| SCHEMBL8532630 | 0.81 | PPARD (0.42) | MCHR1TAOK3TAOK1NPC1LMNA | |
| SCHEMBL8536045 | 0.81 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8531861 | 0.81 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8536706 | 0.81 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8531556 | 0.81 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 | |
| SCHEMBL8533608 | 0.81 | MCHR1 (0.54) | MCHR1NPC1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776365-A | COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST | MITSUI CHEMICALS, INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5725798-A | CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |