Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529539 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HPGDKMT2ATSHRTACR1 | |
| SCHEMBL221145 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL8530014 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL8179017 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL19381543 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2ATSHRTACR1 | |
| SCHEMBL16122122 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2ATSHRTACR1 | |
| SCHEMBL17725702 | 0.76 | KMT2A (0.55) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL8594200 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL311297 | 0.74 | KCNJ1 (0.54) | ALDH1A1HPGDKMT2ATSHRHTT | |
| SCHEMBL12970651 | 0.73 | RXFP1 (0.56) | ALDH1A1HPGDKMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |