Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.41 |
| ▸ | F3 | P13726 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535603 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8536281 | 0.92 | CNR1 (0.52) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8536284 | 0.92 | CNR1 (0.52) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8536826 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8536833 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8536253 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8531915 | 0.77 | HDAC3 (0.54) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL15750407 | 0.77 | HDAC3 (0.54) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8531914 | 0.77 | HDAC3 (0.54) | ALDH1A1CNR1FAAHMAPTCYP19A1 | |
| SCHEMBL8536254 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CNR1FAAHMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801178-A | ACAT INHIBITOR, ARTERIOSCLEROSIS | NIPPON SHOJI KAISH LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0726247-B1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0726247-A1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |