Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434996 | 0.78 | NPSR1 (0.58) | HPGDMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL29059152 | 0.77 | KAT2B (0.47) | HPGDKAT2BSMN1; SMN2CDK8ACVR1 | |
| SCHEMBL19869863 | 0.76 | MEN1 (0.47) | HPGDMEN1KMT2ATBXAS1KAT2B | |
| SCHEMBL1333571 | 0.76 | HPGD (0.55) | HPGDMEN1KMT2ATBXAS1KAT2B | |
| SCHEMBL17559135 | 0.76 | KAT2B (0.50) | HPGDMEN1KMT2ATBXAS1KAT2B | |
| SCHEMBL31091769 | 0.76 | KAT2B (0.50) | HPGDMEN1KMT2ATBXAS1KAT2B | |
| SCHEMBL8864626 | 0.75 | HPGD (0.67) | HPGDMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL823488 | 0.75 | GSK3B (0.45) | HPGDALDH1A1HSD17B10 | |
| SCHEMBL13145736 | 0.73 | HPGD (0.45) | HPGDMEN1KMT2ATBXAS1KAT2B | |
| SCHEMBL12203808 | 0.73 | SMN1; SMN2 (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |