Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542086 | 0.90 | TSHR (0.41) | TSHRLMNATHRB | |
| SCHEMBL6688538 | 0.85 | — | — | |
| SCHEMBL8190611 | 0.79 | — | — | |
| SCHEMBL14446361 | 0.75 | — | — | |
| SCHEMBL6702933 | 0.75 | — | — | |
| SCHEMBL2831677 | 0.75 | — | — | |
| SCHEMBL1337936 | 0.75 | — | — | |
| SCHEMBL1679196 | 0.75 | — | — | |
| SCHEMBL123011 | 0.73 | — | — | |
| SCHEMBL198708 | 0.73 | TSHR (0.39) | TSHRLMNANOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0884311-A2 | Triazole Derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5807806-A | Benzoylpyrazole derivatives having specific substituents and herbicide | NIPPON SODA CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0853626-A1 | SUBSTITUTED PHOSPHINIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997009335-A1 | SUBSTITUTED PHOSPHINIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | NOVARTIS AG (CH) | 1997-03-13 | — | — | WO | disclosed |
| US-5554582-A | Cyclohexenone compounds, their preparation and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| US-5545631-A | GAMMA-AMINOBUTYRIC ACID ANTAGONIST; TREATS PETIT-MAL TYPE EPILEPSIES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0463560-B1 | New antiepileptic agents | CIBA GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |
| US-5424441-A | Nootropic, antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1995-06-13 | — | — | US | disclosed |
| US-5407922-A | GABA antagonists | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| US-5332729-A | Nootropic, antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0569333-A2 | Novel N-aralkyl and N-heteroaralkylamino alcane phosphinic acids | CIBA-GEIGY AG (CH) | 1993-11-10 | — | — | EP | disclosed |
| US-5229379-A | Gamma-aminobutyric acid antagonists | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0319835-B1 | CYCLOHEXENONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AGAINST THE GROWTH OF UNDESIRED PLANTS | BASF Aktiengesellschaft (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0463560-A1 | New antiepileptic agents | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |
| EP-0319835-A2 | Cyclohexenone compounds, process for their preparation and their use against the growth of undesired plants | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |