⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1016347 | 0.92 | — | — | |
| SCHEMBL27819007 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL27990354 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL5586096 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL5586119 | 0.89 | — | — | |
| SCHEMBL2807187 | 0.81 | — | — | |
| SCHEMBL8535684 | 0.75 | TSHR (0.38) | — | |
| Water SCHEMBL27632778 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL24175767 | 0.73 | LMNA (0.43) | — | |
| SCHEMBL21137289 | 0.73 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530420-A | A kind of preparation method of β with optical activation-trifluoromethyl-β-thiofuran ethylene base-beta-amino acids esters compound | 上海应用技术大学 | 2018-09-14 | — | — | CN | claimed |
| US-12258349-B2 | Anti-viral drug | DORING INTERNATIONAL GMBH (CH) | 2025-03-25 | — | — | US | disclosed |
| US-20220298164-A1 | ANTI-VIRAL DRUG | DORING INTERNATIONAL GMBH (CN) | 2022-09-22 | — | — | US | disclosed |
| US-11370797-B2 | Anti-viral drug | DORING INTERNATIONAL GMBH (CH) | 2022-06-28 | — | — | US | disclosed |
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | disclosed |
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |
| CN-101142167-A | Compounds that stimulate glucose utilization and methods of use | UNIV ALBERTA (CA) | 2008-03-12 | — | — | CN | disclosed |
| US-7294369-B2 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-11-13 | — | — | US | disclosed |
| EP-1524308-B1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050227021-A1 | Polymerisable cinnamates with lateral substitution | MERCK PATENT GMBH (DE) | 2005-10-13 | — | — | US | disclosed |
| EP-1524308-A1 | Polymerisable Cinnamates with lateral substitution | MERCK PATENT GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |