Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.44 |
| ▸ | WNT3A | P56704 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728908 | 0.95 | KMT2A (0.58) | KMT2AGSK3BSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL10353860 | 0.85 | NPC1 (0.46) | KMT2AGSK3BSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28342825 | 0.84 | KMT2A (0.55) | KMT2AGSK3BRAB9ANPC1MEN1 | |
| SCHEMBL2118359 | 0.78 | KMT2A (0.60) | KMT2AGSK3BSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL7368111 | 0.78 | NPC1 (0.61) | L3MBTL1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL16552778 | 0.77 | KMT2A (0.83) | KMT2AGSK3BSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL8533727 | 0.77 | GSK3B (0.53) | KMT2AGSK3BHPGDMEN1LMNA | |
| SCHEMBL9733687 | 0.77 | HAO1 (0.43) | KMT2AGSK3BSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL7857467 | 0.77 | KMT2A (0.89) | KMT2AGSK3BSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL10489592 | 0.77 | NPC1 (0.57) | KMT2AGSK3BSMN1; SMN2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |