SCHEMBL2118359

SCHEMBL2118359

Cc1ccc(C(=O)CC[C]=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.60
GSK3B P49841 1/20 0.53
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
MEN1 O00255 3/20 0.50
CTNNB1 P35222 3/20 0.49
WNT3A P56704 3/20 0.49
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
MAPT P10636 1/20 0.46
PAX8 Q06710 1/20 0.45
POLB P06746 1/20 0.45
TP53 P04637 1/20 0.45
THRB P10828 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
ATM Q13315 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16552778 0.83 KMT2A (0.83) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL11728908 0.82 KMT2A (0.58) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL9110538 0.80 GSK3B (0.55) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL11525092 0.80 NPC1 (0.64) KMT2ANPC1RAB9AMEN1CTNNB1
SCHEMBL276675 0.79 TDP1 (0.59) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL3641682 0.79 GSK3B (0.57) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL9419411 0.79 KMT2A (0.69) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL8535836 0.78 KMT2A (0.53) KMT2AGSK3BNPC1RAB9AMEN1
SCHEMBL21051905 0.78 GSR (0.61)
SCHEMBL10854341 0.77 KMT2A (0.67) KMT2AGSK3BNPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140178606-A1 CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-06-26 US disclosed
US-8477275-B2 Optical film and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20130128359-A1 OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2013-05-23 US disclosed
US-8420187-B2 Cellulose acylate composition, cellulose acylate film, and its applications FUJIFILM CORPORATION (JP) 2013-04-16 US disclosed
WO-2013032016-A1 CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-03-07 WO disclosed
US-20120092595-A1 Optical film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120092594-A1 OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20090082557-A1 CELLULOSE ACYLATE FILM AND ITS APPLICATIONS FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090002605-A1 CELLULOSE ACYLATE COMPOSITION, CELLULOSE ACYLATE FILM, AND ITS APPLICATIONS FUJIFILM CORPORATION (JP) 2009-01-01 US disclosed
US-20080241430-A1 CELLULOSE COMPOUND COMPOSITION, CELLULOSE COMPOUND FILM, OPTICALLY COMPENSATORY SHEET, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed