Endothall

Endothall

SCHEMBL8536404

O=C(O)C1C2CCC(O2)C1C(=O)O.O=C(O)C1C2CCC(O2)C1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TFPI2 P48307 7/20 1.00
LMNA P02545 2/20 1.00
KDM4E B2RXH2 1/20 1.00
GMNN O75496 1/20 1.00
PMP22 Q01453 1/20 1.00
TP53 P04637 1/20 1.00
TSHR P16473 1/20 1.00
NFKB1 P19838 1/20 1.00
THPO P40225 1/20 1.00
PPM1B O75688 3/20 0.68
PTPN1 P18031 3/20 0.68
PPP1CC P36873 3/20 0.68
PPP1CA P62136 1/20 0.59
PPP5C P53041 2/20 0.57
PPP2CA P67775 1/20 0.57
NPY4R P50391 1/20 0.57
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
BLM P54132 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Endothall SCHEMBL3494764 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL9464699 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL3495744 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL11394413 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL55158 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL9464559 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL13480837 1.00 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL11143562 0.97 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL29512510 0.97 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL14861262 0.97 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 EP disclosed
WO-1992022203-A1 SUBSTITUTED PYRIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-23 WO disclosed
WO-1992020684-A1 HERBICIDAL OXATRICYCLIC ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-26 WO disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed
WO-1992010501-A1 HERBICIDAL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
WO-1992009587-A1 HERBICIDAL OXAZINE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed
WO-1992004827-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
EP-0463054-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP disclosed
WO-1991010668-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed
EP-0432200-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-19 EP disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 WO disclosed
WO-1990010634-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-20 WO disclosed
EP-0386001-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-12 EP disclosed
EP-0368897-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-23 EP disclosed
WO-1990002486-A1 WATER-SOLUBLE OR WATER-DISPERSIBLE PESTICIDE GRANULES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-22 WO disclosed
WO-1989002700-A2 HERBICIDAL O-CARBOMETHOXYSULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-06 WO disclosed
WO-1989000991-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-09 WO disclosed
WO-1989000994-A2 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-09 WO disclosed