Endothall

Endothall

SCHEMBL11143562

O=C(O)C1C2CCC(O2)C1C(=O)O.[KH].[KH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TFPI2 P48307 7/20 0.94
LMNA P02545 2/20 0.94
KDM4E B2RXH2 1/20 0.94
GMNN O75496 1/20 0.94
PMP22 Q01453 1/20 0.94
TP53 P04637 1/20 0.94
TSHR P16473 1/20 0.94
NFKB1 P19838 1/20 0.94
THPO P40225 1/20 0.94
PPM1B O75688 3/20 0.65
PTPN1 P18031 3/20 0.65
PPP1CC P36873 3/20 0.65
PPP1CA P62136 1/20 0.57
PPP5C P53041 2/20 0.55
PPP2CA P67775 1/20 0.55
NPY4R P50391 1/20 0.55
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Endothall SCHEMBL8466779 0.97 TFPI2 (0.90) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL9464559 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL3495744 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL11394413 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL55158 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL13480837 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL9464699 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL8536404 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL3494764 0.97 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL29512510 0.94 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4401456-A DROPPING AQUEOUS SOLUTION OF ALGINATE AND PESTICIDE INTO AQUEOUS CALCIUM-, BARIUM-, OR COPPER-CHLORIDE SOLUTION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1983-08-30 US disclosed
US-4400391-A GELATION OF DROPS OF A DISPERSION OF ALGINATE AND INSECTICIDE BY AN AQUEOUS SOLUTION OF METAL COMPOUND THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1983-08-23 US disclosed