Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533046 | 1.00 | MCL1 (0.49) | MCL1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL8533043 | 1.00 | MCL1 (0.49) | MCL1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL11037176 | 0.91 | SMN1; SMN2 (0.44) | MCL1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL597525 | 0.90 | SMN1; SMN2 (0.44) | MCL1SMN1; SMN2MEN1KMT2ACNR2 | |
| SCHEMBL597524 | 0.90 | SMN1; SMN2 (0.44) | MCL1SMN1; SMN2MEN1KMT2ACNR2 | |
| SCHEMBL598825 | 0.90 | SMN1; SMN2 (0.44) | MCL1SMN1; SMN2MEN1KMT2ACNR2 | |
| SCHEMBL38246 | 0.90 | MCL1 (0.50) | MCL1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL8014971 | 0.88 | MCL1 (0.57) | MCL1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL38409 | 0.88 | MCL1 (0.57) | MCL1SMN1; SMN2MEN1KMT2ADDB1 | |
| SCHEMBL8645790 | 0.87 | MCL1 (0.55) | MCL1SMN1; SMN2MEN1KMT2ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746426-B2 | Stabilization of a co-bound intermediate via molecular tuning promotes CO2-to-ethylene conversion | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-05 | — | — | US | disclosed |
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |