SCHEMBL11037176

SCHEMBL11037176

O=C1CCC(C(=O)c2ccc(C(=O)C3CCC(=O)N3)cc2)N1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 2/20 0.42
GAA P10253 1/20 0.42
LMNA P02545 1/20 0.38
DDB1 Q16531 3/20 0.38
CRBN Q96SW2 3/20 0.38
MCL1 Q07820 1/20 0.37
CNR2 P34972 1/20 0.36
IKZF3 Q9UKT9 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
NAMPT P43490 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11311666 0.91 MGLL (0.43) SMN1; SMN2MEN1KMT2ALMNADDB1
SCHEMBL8536487 0.91 MCL1 (0.49) SMN1; SMN2MEN1KMT2APOLBGAA
SCHEMBL8533046 0.91 MCL1 (0.49) SMN1; SMN2MEN1KMT2APOLBGAA
SCHEMBL8533043 0.91 MCL1 (0.49) SMN1; SMN2MEN1KMT2APOLBGAA
SCHEMBL8028222 0.89 MCL1 (0.39) SMN1; SMN2MEN1KMT2APOLBGAA
SCHEMBL597524 0.88 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2AMCL1CNR2
SCHEMBL597525 0.88 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2AMCL1CNR2
SCHEMBL598825 0.88 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2AMCL1CNR2
SCHEMBL8532277 0.88 SMN1; SMN2 (0.45) SMN1; SMN2MEN1KMT2APOLBGAA
SCHEMBL993051 0.87 MCL1 (0.45) SMN1; SMN2MEN1KMT2APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0009950-B1 BLOCK COPOLYMER HOT MELT ADHESIVE COMPOSITION AND METHOD OF FILLING A CAVITY MONSANTO COMPANY (US) 1984-04-18 EP disclosed
EP-0009949-B1 BLOCK COPOLYMER HOT MELT ADHESIVE COMPOSITIONS, A METHOD OF FILLING A CAVITY IN A SUBSTRATE THEREWITH, AND A SUBSTRATE WITH A CAVITY FILLED WITH SUCH A COMPOSITION MONSANTO COMPANY (US) 1984-03-21 EP disclosed
EP-0009937-B1 BLOCK COPOLYMER HOT MELT ADHESIVE COMPOSITIONS, A METHOD OF FILLING A CAVITY THEREWITH, AND A SUBSTRATE WITH A CAVITY FILLED WITH SUCH A COMPOSITION MONSANTO COMPANY (US) 1983-10-12 EP disclosed
US-4252712-A COMPRISING ALUMINUM POWDER, GLASS FIBER, HOLLOW SILICATE MICROSPHERES, AND POLYESTERS-AMIDES AND/OR -ETHERS; FILLING AND COATING SUBSTRATES; AUTOS AND APPLIANCES MONSANTO COMPANY (US) 1981-02-24 US disclosed
US-4222976-A BLOCK COPOLYMERS (ESTERS, ETHERS, AMIDES), ALUMINUM POWDER AND GLASS FIBERS MONSANTO COMPANY (US) 1980-09-16 US disclosed
US-4219459-A POLYESTERS, POLYAMIDES, POLYETHERS; FILLING CAVITIES IN SUBSTRATES MONSANTO COMPANY (US) 1980-08-26 US disclosed
US-4219458-A POLYESTERS-AMIDES-ETHERS, ALUMINUM POWDER, GLASS FIBERS MONSANTO COMPANY (US) 1980-08-26 US disclosed
US-4219460-A POLYESTERS, POLYAMIDES, POLYETHERS; USED FOR FILLING CAVITIES IN SUBSTRATES MONSANTO COMPANY (US) 1980-08-26 US disclosed
US-4217376-A Cavity filling with a hot melt adhesive composition MONSANTO COMPANY (US) 1980-08-12 US disclosed
US-4215159-A BLOCK POLYMER, MINERAL REINFORCEMENT, GLASS FIBERS MONSANTO COMPANY (US) 1980-07-29 US disclosed
US-4214019-A Cavity filling with a hot melt adhesive composition MONSANTO COMPANY (US) 1980-07-22 US disclosed
EP-0009937-A1 Block copolymer hot melt adhesive compositions, a method of filling a cavity therewith, and a substrate with a cavity filled with such a composition MONSANTO COMPANY (US) 1980-04-16 EP disclosed
EP-0009950-A1 Block copolymer hot melt adhesive composition and method of filling a cavity MONSANTO COMPANY (US) 1980-04-16 EP disclosed
EP-0009949-A1 Block copolymer hot melt adhesive compositions, a method of filling a cavity in a substrate therewith, and a substrate with a cavity filled with such a composition MONSANTO COMPANY (US) 1980-04-16 EP disclosed