Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531818 | 0.98 | HRH3 (0.45) | HRH3HRH1HTR2AHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8535833 | 0.97 | HRH3 (0.44) | HRH3HRH1HTR2AHTR1ADRD2 | |
| Fumaric Acid SCHEMBL29737159 | 0.87 | MCHR1 (0.38) | HRH3HRH1HTR2AHTR1ADRD2 | |
| SCHEMBL8533134 | 0.85 | HRH3 (0.42) | HRH3HRH1HTR2AHTR1ADRD2 | |
| SCHEMBL8535845 | 0.85 | HRH3 (0.39) | HRH3HRH1HTR2AHTR1ADRD2 | |
| SCHEMBL8533481 | 0.83 | MCHR1 (0.41) | HRH3HRH1HTR2AHTR1ADRD2 | |
| SCHEMBL8531503 | 0.81 | HTR2A (0.41) | HRH3HRH1HTR2AHTR1ADRD2 | |
| SCHEMBL8536618 | 0.81 | HTR2C (0.43) | HRH3HRH1HTR2AHTR1ADRD2 | |
| SCHEMBL8531883 | 0.80 | MCHR1 (0.41) | HRH3HTR2CMCHR1SMN1; SMN2CYP1A2 | |
| SCHEMBL8535500 | 0.80 | HRH3 (0.44) | HRH3HRH1HTR2AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| CN-1187811-A | 1-[omega-(3,4-dihydro-2-naphthalenyl) alkyl] cyclic amine derivatives, process for producing same, and medicinal composition containing same | DAINIPPON PHARMACEUTICAL CO (JP) | 1998-07-15 | — | — | CN | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |