Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533481 | 0.87 | MCHR1 (0.41) | MCHR1MEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL8535840 | 0.83 | ALDH1A1 (0.46) | MCHR1MEN1KMT2AALDH1A1HTR2C | |
| SCHEMBL8531818 | 0.81 | HRH3 (0.45) | MCHR1ALDH1A1HTR2CKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8535833 | 0.80 | HRH3 (0.44) | MCHR1ALDH1A1HTR2CKDM4ESMN1; SMN2 | |
| SCHEMBL8536585 | 0.80 | HRH3 (0.44) | MCHR1HTR2CKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL27482748 | 0.78 | PRPS1 (0.34) | MCHR1 | |
| SCHEMBL8533134 | 0.77 | HRH3 (0.42) | HTR2CKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL8535845 | 0.77 | HRH3 (0.39) | MCHR1HTR2CCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8535500 | 0.75 | HRH3 (0.44) | HTR2CHRH3 | |
| SCHEMBL8531503 | 0.74 | HTR2A (0.41) | MCHR1HTR2CCYP1A2CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |