Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.82 |
| ▸ | BCR | P11274 | 2/20 | 0.82 |
| ▸ | ESR1 | P03372 | 14/20 | 0.81 |
| ▸ | ESR2 | Q92731 | 14/20 | 0.81 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014459 | 0.95 | ABL1 (0.91) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL30275026 | 0.95 | ESR2 (0.90) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL5425451 | 0.95 | ESR2 (0.90) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL3016969 | 0.91 | ABL1 (0.83) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL1741908 | 0.90 | ABL1 (1.00) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL21729891 | 0.90 | ESR1 (0.87) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL29991899 | 0.90 | ESR1 (1.00) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL2699234 | 0.90 | ESR1 (1.00) | ABL1ABCB1BCRESR1ESR2 | |
| Methane SCHEMBL5526746 | 0.87 | ESR1 (0.95) | ABL1ABCB1BCRESR1ESR2 | |
| SCHEMBL516421 | 0.86 | ESR1 (0.90) | ABL1ABCB1BCRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841471-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | GRACE W R & CO (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20190153135-A1 | Activator Compositions, Their Preparation, And Their Use In Catalysts | GRACE W R & CO (US) | 2019-05-23 | — | — | US | disclosed |
| US-10221264-B2 | Activator compositions, their preparation, and their use in catalysts | W. R. GRACE & CO.-CONN. (US) | 2019-03-05 | — | — | US | disclosed |
| CN-103380154-B | Activator composition, its preparation and the purposes in catalysis thereof | 阿尔比马尔公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104854150-A | Activator compositions, their preparation, and their use in catalysts | ALBEMARLE CORP | 2015-08-19 | — | — | CN | disclosed |
| US-20150105238-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | W. R. GRACE & CO.-CONN. | 2015-04-16 | — | — | US | disclosed |
| EP-2643366-B1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORP (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2841471-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | Albemarle Corporation (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8895465-B2 | Activator compositions, their preparation, and their use in catalysis | ALBEMARLE CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |
| WO-2013162745-A1 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSTS | ALBEMARLE CORPORATION (US) | 2013-10-31 | — | — | WO | disclosed |
| EP-2643366-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | Albemarle Corporation (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20130253155-A1 | Activator Compositions, Their Preparation, and Their Use In Catalysis | ALBEMARIE CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012071205-A2 | ACTIVATOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORPORATION (US) | 2012-05-31 | — | — | WO | disclosed |