SCHEMBL5425451

SCHEMBL5425451

Oc1ccc2cc(-c3ccc4cc(O)ccc4c3)ccc2c1

nearest known ligand 0.90

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 14/20 0.90
ESR1 P03372 13/20 0.90
ABL1 P00519 2/20 0.81
ABCB1 P08183 2/20 0.81
BCR P11274 2/20 0.81
HSD17B1 P14061 2/20 0.77
CYP1A2 P05177 2/20 0.77
CYP3A4 P08684 1/20 0.77
CYP2D6 P10635 1/20 0.77
CYP2C9 P11712 1/20 0.77
CYP2B6 P20813 1/20 0.77
CYP2C19 P33261 1/20 0.77
HSD17B2 P37059 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30275026 1.00 ESR2 (0.90) ESR2ESR1ABL1ABCB1BCR
SCHEMBL29991899 0.95 ESR1 (1.00) ESR2ESR1ABL1ABCB1BCR
SCHEMBL2699234 0.95 ESR1 (1.00) ESR2ESR1ABL1ABCB1BCR
SCHEMBL8536612 0.95 ABL1 (0.82) ESR2ESR1ABL1ABCB1BCR
Methane SCHEMBL5526746 0.92 ESR1 (0.95) ESR2ESR1ABL1ABCB1BCR
SCHEMBL516421 0.92 ESR1 (0.90) ESR2ESR1ABL1ABCB1BCR
SCHEMBL14506125 0.90 ESR2 (0.83) ESR2ESR1ABL1ABCB1BCR
SCHEMBL1741908 0.90 ABL1 (1.00) ESR2ESR1ABL1ABCB1BCR
SCHEMBL21729891 0.90 ESR1 (0.87) ESR2ESR1ABL1ABCB1BCR
SCHEMBL3107306 0.90 ESR2 (0.83) ESR2ESR1ABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291122-A Anionic curable composition 设计分子有限公司 2018-07-17 CN claimed
JP-6032893-A None JP disclosed
JP-6025400-A None JP disclosed
US-11069557-B2 Method for producing thin wafer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-07-20 US disclosed
EP-3618102-B1 METHOD FOR PRODUCING THIN WAFER SHINETSU CHEMICAL CO (JP) 2021-05-19 EP disclosed
US-10886119-B2 Aromatic underlayer ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2021-01-05 US disclosed
US-10727103-B2 Semiconductor device, method for producing the same, and laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
US-10658314-B2 Wafer laminate, method for production thereof, and adhesive composition for wafer laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-19 US disclosed
EP-3467069-B1 SEMICONDUCTOR DEVICE, METHOD FOR PRODUCING THE SAME, AND LAMINATE SHINETSU CHEMICAL CO (JP) 2020-04-29 EP disclosed
US-20200075388-A1 METHOD FOR PRODUCING THIN WAFER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-05 US disclosed
US-8674138-B2 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same LG CHEM. LTD. (KR) 2014-03-18 US disclosed
US-20070108892-A1 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same LG CHEM. LTD. (KR) 2007-05-17 US disclosed
US-20070108892-A1 Binaphthalene derivatives, preparation method thereof and organic electronic device using the same LG CHEM. LTD. (KR) 2007-05-17 US disclosed
WO-2007046658-A1 NEW BINAPHTHALENE DERIVATIVES, PREPARATION METHOD THEREOF AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM. LTD. (KR) 2007-04-26 WO disclosed
US-20070015813-A1 Treatment of protein folding disorders QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-01-18 US disclosed
US-20070015813-A1 Treatment of protein folding disorders QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-01-18 US disclosed
US-20070015813-A1 Treatment of protein folding disorders QUEEN'S UNIVERSITY AT KINGSTON (CA) 2007-01-18 US disclosed
US-20030092637-A1 Novel compounds XYLOGEN AB (SE) 2003-05-15 US disclosed
JP-H0632893-A AROMATIC POLYESTER AND ITS PRODUCTION IDEMITSU KOSAN CO LTD 1994-02-08 JP disclosed
JP-H0625400-A POLYCARBONATE AND ITS PRODUCTION IDEMITSU KOSAN CO LTD 1994-02-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092637-A1 Novel compounds ENTPD5, G6PD, G6PC1 ESR2 3677/4885ESR1 4428/4885ABL1 2226/4885
US-20070015813-A1 Treatment of protein folding disorders HSPA5, TTR, TUFM ESR2 3195/4885ESR1 3985/4885ABL1 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.