Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.65 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896604 | 0.98 | LTA4H (0.67) | LTA4HKCNA3PLA2G2AHDAC1HDAC2 | |
| SCHEMBL5375466 | 0.92 | LTA4H (0.68) | LTA4HKCNA3PLA2G2AHDAC1HDAC2 | |
| SCHEMBL1172113 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL7562039 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL7008145 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL23014989 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL1171574 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL9169690 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL7612512 | 0.92 | KCNA3 (0.73) | LTA4HKCNA3HDAC1HDAC2HDAC3 | |
| SCHEMBL311427 | 0.90 | KCNA3 (0.76) | LTA4HKCNA3HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750532-A | TETRAHYDROPYRIMIDINE-2,4-DIONE DERIVATIVES, VIRICIDES, ANTIINFLAMMATORY AGENTS, PAF INHIBITORS | SCHERING CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| US-5272167-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0560407-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1991000858-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | SCHERING CORPORATION (US) | 1991-01-24 | — | — | WO | disclosed |
| EP-0407217-A1 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1991-01-09 | — | — | EP | disclosed |
| US-4851423-A | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |