Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MYOC | Q99972 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39135 | 1.00 | HSPB1 (0.51) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| Nitrofen SCHEMBL5921708 | 0.90 | PDE7A (0.60) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL135528 | 0.89 | HSPB1 (0.53) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL30606813 | 0.89 | HSPB1 (0.53) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL3990252 | 0.87 | PDE7A (0.49) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL3986085 | 0.87 | HTT (0.53) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL11591880 | 0.87 | PDE7A (0.60) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL9674617 | 0.86 | PDE7A (0.50) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL8504005 | 0.85 | PDE7A (0.43) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL5387132 | 0.84 | PTPN7 (0.58) | HSPB1PDE7AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| WO-1992013861-A1 | HERBICIDAL BICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |
| WO-1992010501-A1 | HERBICIDAL ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009587-A1 | HERBICIDAL OXAZINE ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009578-A1 | SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |