SCHEMBL8536738

SCHEMBL8536738

CCCCCCCCCCOc1ccc(-c2ccc3cc2-3)cc1.O=C(O)c1ccc2c(c1)CCC(C(=O)O)C2

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 2/20 0.53
RARB P10826 4/20 0.52
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
PLA2G4B P0C869 5/20 0.48
S1PR1 P21453 5/20 0.45
S1PR5 Q9H228 5/20 0.45
S1PR3 Q99500 4/20 0.45
PLA2G4A P47712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8531556 0.83 MCHR1 (0.54) RARBTP53TSHRPLA2G4BS1PR1
SCHEMBL8533685 0.83 MCHR1 (0.54) RARBTP53TSHRPLA2G4BS1PR1
SCHEMBL8533608 0.83 MCHR1 (0.54) RARBTP53TSHRPLA2G4BS1PR1
SCHEMBL8536045 0.83 MCHR1 (0.54) RARBTP53TSHRPLA2G4BS1PR1
SCHEMBL8536706 0.83 MCHR1 (0.54) RARBTP53TSHRPLA2G4BS1PR1
SCHEMBL8531861 0.83 MCHR1 (0.54) RARBTP53TSHRPLA2G4BS1PR1
SCHEMBL9695400 0.83 FFAR1 (0.54) TP53TSHRS1PR1S1PR5S1PR3
SCHEMBL7604793 0.83 FFAR1 (0.54) TP53TSHRS1PR1S1PR5S1PR3
SCHEMBL9441318 0.83 FFAR1 (0.54) TP53TSHRS1PR1S1PR5S1PR3
SCHEMBL8536472 0.82 NPC1 (0.50) RARBTP53TSHRPLA2G4BS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776365-A COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST MITSUI CHEMICALS, INC. (JP) 1998-07-07 US disclosed
US-5725798-A CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US disclosed