Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699261 | 0.84 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL270008 | 0.80 | — | — | |
| 2-Pyridinecarboxaldehyde SCHEMBL27465297 | 0.78 | MEN1 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL18228880 | 0.76 | MEN1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5664412 | 0.75 | KDM4E (0.41) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL96245 | 0.75 | MEN1 (0.54) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL2643842 | 0.73 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL498505 | 0.72 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL4380612 | 0.72 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL5665933 | 0.72 | KDM4E (0.39) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107027309-B | Antibacterial agent | 昆士兰大学 | 2021-10-01 | — | — | CN | disclosed |
| US-10947271-B2 | Antibacterial agents | THE UNIVERSITY OF QUEENSLAND (AU) | 2021-03-16 | — | — | US | disclosed |
| US-20170204138-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-07-20 | — | — | US | disclosed |
| EP-3105244-A1 | ANTIBACTERIAL AGENTS | The University Of Queensland (AU) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015117196-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-08-13 | — | — | WO | disclosed |
| EP-0807098-B1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | DU PONT (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5741955-A | TRANSITION METAL COMPLEX CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0807098-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996023753-A1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204138-A1 | ANTIBACTERIAL AGENTS | VNN1, ASNS, AAAS | NPC1 1791/4885RAB9A 2995/4885MEN1 3291/4885 |
| US-10947271-B2 | Antibacterial agents | VNN1, ASNS, AAAS | NPC1 1791/4885RAB9A 2995/4885MEN1 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.