Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531340 | 0.87 | TSHR (0.39) | MAPTALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL5642200 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL31503647 | 0.83 | GAA (0.40) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7138352 | 0.83 | MAPT (0.40) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL5562501 | 0.81 | MAPT (0.59) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL26930698 | 0.78 | MAPT (0.61) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL9781225 | 0.78 | NPC1 (0.50) | TSHRGAAPPOXHTR2AHTR2C | |
| SCHEMBL23914752 | 0.77 | MAPT (0.44) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL23914959 | 0.77 | MAPT (0.51) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL23913686 | 0.77 | MAPT (0.43) | MAPTALDH1A1TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786301-A | HERBICIDES | ZENECA LIMITED (GB) | 1998-07-28 | — | — | US | disclosed |