Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542830 | 0.82 | PDE4A (0.39) | KMT2ACDC7DBF4PIK3CDPIK3R1 | |
| SCHEMBL8537120 | 0.81 | CYP1A2 (0.47) | SMN1; SMN2BRAFCYP1A2GAAXDH | |
| SCHEMBL1286947 | 0.81 | MAPK1 (0.51) | SMN1; SMN2CYP1A2KMT2APIK3CDPIK3R1 | |
| Hydrochloric Acid SCHEMBL21799343 | 0.80 | MAPK1 (0.50) | SMN1; SMN2CYP1A2KMT2APIK3CDPIK3R1 | |
| SCHEMBL1286944 | 0.78 | PNP (0.38) | SMN1; SMN2GAAHTTCDC7PIK3CD | |
| SCHEMBL27881956 | 0.76 | PDE4A (0.41) | HTTPIK3CD | |
| SCHEMBL3310029 | 0.74 | HCAR1 (0.46) | BRAFCYP1A2GAACDC7DBF4 | |
| SCHEMBL11610799 | 0.73 | DPP4 (0.44) | BRAFPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL1286959 | 0.71 | HCAR1 (0.49) | SMN1; SMN2HTTMEN1KMT2APIK3CG | |
| SCHEMBL9235123 | 0.71 | PNP (0.47) | KMT2ACDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |