Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532499 | 0.94 | EPHX2 (0.60) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8537601 | 0.92 | SOAT1 (0.52) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8537603 | 0.92 | SOAT1 (0.52) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8533581 | 0.86 | SOAT1 (0.61) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8533580 | 0.86 | SOAT1 (0.61) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8532492 | 0.83 | SOAT1 (0.55) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8532494 | 0.83 | SOAT1 (0.55) | EPHX2CNR1FAAHCNR2SOAT1 | |
| SCHEMBL8533117 | 0.81 | SOAT1 (0.70) | EPHX2CNR1FAAHSOAT1ALDH1A1 | |
| SCHEMBL8533118 | 0.81 | SOAT1 (0.70) | EPHX2CNR1FAAHSOAT1ALDH1A1 | |
| SCHEMBL8537165 | 0.80 | SOAT1 (0.47) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801178-A | ACAT INHIBITOR, ARTERIOSCLEROSIS | NIPPON SHOJI KAISH LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0726247-B1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0726247-A1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |