Nitrofluorfen

Nitrofluorfen

SCHEMBL8537296

O=[N+]([O-])c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1.O=[N+]([O-])c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
TTR P02766 1/20 0.63
PPOX P50336 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
PDE7A Q13946 1/20 0.60
FFAR1 O14842 5/20 0.55
HSPB1 P04792 3/20 0.52
GAA P10253 1/20 0.52
PKM P14618 1/20 0.52
MAPT P10636 3/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrofluorfen SCHEMBL39312 1.00 MEN1 (0.63) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL29370618 1.00 MEN1 (0.63) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL11297390 0.99 MEN1 (0.62) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL11297383 0.99 MEN1 (0.62) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL9674232 0.95 MEN1 (0.58) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL10963788 0.93 MEN1 (0.56) MEN1KMT2ATTRPPOXTDP1
SCHEMBL10684747 0.89 PDE7A (0.58) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL11115864 0.89 MEN1 (0.53) MEN1KMT2ATTRPPOXTDP1
Nitrofluorfen SCHEMBL11129292 0.87 MEN1 (0.53) MEN1KMT2ATTRPPOXTDP1
SCHEMBL11095176 0.85 FFAR1 (0.65) MEN1KMT2ATTRPPOXTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed
WO-1992013861-A1 HERBICIDAL BICYCLIC ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-20 WO disclosed
WO-1992010501-A1 HERBICIDAL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
WO-1992009587-A1 HERBICIDAL OXAZINE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed
WO-1992009578-A1 SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed
WO-1992004827-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
WO-1991010653-A1 HERBICIDAL PYRIMIDINES AND TRIAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed
WO-1991010668-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed