SCHEMBL11095176

SCHEMBL11095176

FC(F)(F)c1ccc(Oc2ccc(Oc3ccc(C(F)(F)F)cc3Cl)cc2)c(Cl)c1

nearest known ligand 0.84

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.65
MEN1 O00255 1/20 0.56
TTR P02766 1/20 0.56
PPOX P50336 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.54
RAB9A P51151 1/20 0.54
HTR2A P28223 6/20 0.51
SLC6A4 P31645 6/20 0.51
KCNH2 Q12809 6/20 0.51
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
ATM Q13315 1/20 0.50
MRGPRX4 Q96LA9 2/20 0.47
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10969104 0.95 FFAR1 (0.60) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL15384989 0.92 HTR2A (0.59) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL2892190 0.92 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8684467 0.92 FFAR1 (0.61) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL8684464 0.92 FFAR1 (0.61) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9582439 0.92 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL11238861 0.92 L3MBTL1 (0.68) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL12937232 0.92 FFAR1 (0.58) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9003844 0.91 FFAR1 (0.60) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL13506726 0.90 FFAR1 (0.56) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465503-A Diphenyl ether derivatives, process for preparing the same and herbicidal compositions containing the same UBE INDUSTRIES LTD. (JP) 1984-08-14 US disclosed
EP-0023725-B1 DIPHENYL ETHER DERIVATIVES, PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME UBE INDUSTRIES, LTD. (JP) 1982-03-31 EP disclosed
EP-0023725-A1 Diphenyl ether derivatives, process for preparing the same and herbicidal compositions containing the same UBE INDUSTRIES, LTD. (JP) 1981-02-11 EP disclosed
US-4172959-A Process for the manufacture of diphenyl ethers HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-30 US disclosed
US-4070178-A Herbicidal diphenyl ethers ROHM AND HAAS COMPANY (US) 1978-01-24 US disclosed