Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355285 | 1.00 | LMNA (0.64) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL65969 | 1.00 | LMNA (0.64) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL27797742 | 0.96 | LMNA (0.60) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL27859402 | 0.91 | LMNA (0.53) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| Terbuthylazine SCHEMBL17841769 | 0.88 | KMT2A (0.57) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL761988 | 0.86 | GAA (0.61) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL762576 | 0.86 | GAA (0.55) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL6716129 | 0.86 | GAA (0.61) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL28205630 | 0.85 | LMNA (0.47) | LMNAGAACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL8333505 | 0.85 | GAA (0.51) | LMNAGAACYP1A2CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| WO-1992020684-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
| WO-1992013861-A1 | HERBICIDAL BICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |
| WO-1992009578-A1 | SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |