Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483028 | 1.00 | TLR9 (0.40) | TLR9TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11032610 | 1.00 | TLR9 (0.40) | TLR9TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31231840 | 0.87 | TLR9 (0.47) | TLR9TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8186025 | 0.84 | TLR9 (0.38) | TLR9SLC6A2SLC6A4SLC6A3CTRB1 | |
| SCHEMBL24572017 | 0.83 | TSHR (0.61) | TSHRSLC6A2TAAR1LMNAHTR1A | |
| SCHEMBL13941992 | 0.83 | TSHR (0.61) | TSHRSLC6A2TAAR1LMNAHTR1A | |
| SCHEMBL24215035 | 0.83 | TSHR (0.61) | TSHRSLC6A2TAAR1LMNAHTR1A | |
| SCHEMBL9679098 | 0.83 | TSHR (0.61) | TSHRSLC6A2TAAR1LMNAHTR1A | |
| SCHEMBL2386075 | 0.83 | TSHR (0.61) | TSHRSLC6A2TAAR1LMNAHTR1A | |
| SCHEMBL7173277 | 0.80 | MEN1 (0.44) | TLR9TSHRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57116060-A | — | — | None | — | — | JP | disclosed |
| EP-0438796-B1 | Process for the enantioselection synthesis of alkylated oxindoles used as intermediates in the preparation of physostigmine | HOECHST MARION ROUSSEL INC (US) | 1998-08-26 | — | — | EP | disclosed |
| JP-S57116060-A | PREPARATION OF (R)-(-)-5- BENZYLOXYMETHYLTETRAHYDROFURAN-2-ONE | KAWAKEN FINE CHEM CO LTD | 1982-07-19 | — | — | JP | disclosed |