Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750411 | 0.85 | MEN1 (0.51) | MEN1KMT2APDE4DSLC6A2SLC6A4 | |
| SCHEMBL31231840 | 0.83 | TLR9 (0.47) | SLC6A2SLC6A4SLC6A3TLR9FASN | |
| SCHEMBL11032610 | 0.80 | TLR9 (0.40) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8483028 | 0.80 | TLR9 (0.40) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8537354 | 0.80 | TLR9 (0.40) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7173273 | 0.78 | TLR9 (0.42) | PDE4DSLC6A2SLC6A4SLC6A3TLR9 | |
| SCHEMBL27810885 | 0.75 | PDE4D (0.51) | MEN1KMT2APDE4DTSHRTAAR1 | |
| SCHEMBL27344249 | 0.74 | ALDH1A1 (0.38) | SLC6A2SLC6A4SLC6A3TLR9TSHR | |
| SCHEMBL8310780 | 0.74 | TSHR (0.42) | PDE4DSLC6A2SLC6A4SLC6A3TLR9 | |
| SCHEMBL1493181 | 0.74 | TSHR (0.42) | PDE4DSLC6A2SLC6A4SLC6A3TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988789-B1 | Reduced pitting microbicide formulation | ROHM & HAAS (US) | 2003-08-27 | — | — | EP | claimed |