Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADH5 | P11766 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537461 | 0.79 | LSS (0.48) | SLC9A1LSSGPR119HTR2AHTR2C | |
| SCHEMBL8537654 | 0.77 | HTR2A (0.59) | SLC9A1LSSGPR119HTR2AHTR2C | |
| SCHEMBL4723273 | 0.76 | F10 (0.56) | SLC9A1LSSGPR119HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8539581 | 0.76 | HTR2A (0.58) | SLC9A1LSSGPR119HTR2AHTR2C | |
| SCHEMBL8536934 | 0.74 | HTR2A (0.60) | SLC9A1LSSGPR119HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8537801 | 0.74 | HTR2A (0.59) | SLC9A1LSSGPR119HTR2AHTR2C | |
| SCHEMBL4723269 | 0.73 | HTR2A (0.57) | SLC9A1LSSGPR119HTR2AHTR2C | |
| SCHEMBL8534514 | 0.72 | HTR2A (0.51) | SLC9A1LSSGPR119HTR2AHTR2C | |
| SCHEMBL9363641 | 0.72 | HPGD (0.68) | LSSHTR2AHTR2CHTR2BMAPT | |
| SCHEMBL8535599 | 0.71 | LSS (0.50) | SLC9A1LSSGPR119HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537201-B1 | 1-[4-(IMIDAZOL-1-YL)BENZOYL]PIPERIDINE DERIVATIVES AS ANTIARRHYTHMIC AGENTS | SCHERING AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0537201-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1991019709-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-26 | — | — | WO | disclosed |