Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | LSS | P48449 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ADH5 | P11766 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9368954 | 0.99 | HPGD (0.66) | HPGDKMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8536306 | 0.83 | LSS (0.60) | HPGDLSSCYP3A4BAZ2BHTT | |
| Hydrochloric Acid SCHEMBL5734554 | 0.82 | LSS (0.59) | HPGDLSSCYP3A4BAZ2BHTT | |
| SCHEMBL8536934 | 0.82 | HTR2A (0.60) | HPGDKMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8537654 | 0.81 | HTR2A (0.59) | HPGDLSSCYP3A4BAZ2BHTT | |
| Hydrochloric Acid SCHEMBL8537801 | 0.81 | HTR2A (0.59) | HPGDKMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9524355 | 0.80 | LSS (0.54) | HPGDKMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18848731 | 0.80 | DRD3 (0.51) | KMT2ALSSCYP3A4BAZ2BHTT | |
| SCHEMBL10562129 | 0.80 | LSS (0.60) | HPGDKMT2ACYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL8539581 | 0.80 | HTR2A (0.58) | HPGDLSSCYP3A4BAZ2BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | claimed |
| US-4804662-A | Substituted 4-(1H-imidazol-1-yl)benzamides as antiarrhythmic agents | SCHERING A.G. (DE) | 1989-02-14 | — | — | US | claimed |
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| US-4804662-A | Substituted 4-(1H-imidazol-1-yl)benzamides as antiarrhythmic agents | SCHERING A.G. (DE) | 1989-02-14 | — | — | US | disclosed |