Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539801 | 0.95 | LTA4H (0.55) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL8539823 | 0.89 | LTA4H (0.57) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL10674759 | 0.84 | HRH3 (0.57) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL8536500 | 0.83 | KCNA3 (0.58) | HRH3HDAC1HDAC2LTA4HKCNA3 | |
| SCHEMBL95473 | 0.82 | KCNA3 (0.76) | HDAC1HDAC2LTA4HKCNA3HDAC3 | |
| SCHEMBL10671455 | 0.82 | HRH3 (0.60) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL4894683 | 0.82 | HRH3 (0.56) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL10681293 | 0.82 | HRH3 (0.60) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL10679229 | 0.82 | HRH3 (0.56) | HRH3HDAC1HDAC2LTA4HBACE1 | |
| SCHEMBL10683208 | 0.82 | HRH3 (0.60) | HRH3HDAC1HDAC2LTA4HBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |