Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 19/20 | 1.00 |
| ▸ | OGFRL1 | Q5TC84 | 19/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 17/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853749 | 1.00 | OPRM1 (1.00) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL853944 | 1.00 | OPRM1 (1.00) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL880768 | 0.87 | OGFRL1 (1.00) | OPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL13221996 | 0.87 | OGFRL1 (1.00) | OPRM1OPRK1OGFRL1OPRD1 | |
| SCHEMBL852647 | 0.83 | OPRM1 (1.00) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL852648 | 0.83 | OPRM1 (1.00) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL21548113 | 0.83 | OPRM1 (1.00) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL16731368 | 0.82 | OGFRL1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL16382116 | 0.82 | OGFRL1 (0.70) | OPRM1OPRK1OGFRL1OPRD1OPRL1 | |
| SCHEMBL852096 | 0.81 | OPRM1 (1.00) | OPRM1OPRK1OGFRL1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-3101018-A1 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | Purdue Pharma L.P. (US) | 2016-12-07 | — | — | EP | disclosed |
| EP-2433937-B1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | PURDUE PHARMA LP (US) | 2016-06-29 | — | — | EP | disclosed |
| EP-2086958-B1 | SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2015-01-14 | — | — | EP | disclosed |
| EP-2433937-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433935-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2433936-A1 | Substituted-quinoxaline-type-piperidine compounds and the uses thereof | Purdue Pharma LP (US) | 2012-03-28 | — | — | EP | disclosed |