SCHEMBL8537683

SCHEMBL8537683

CCC[SiH]1CCC(C2CCC(c3cc(F)c(-c4ccc(OC(F)(F)F)cc4)c(F)c3)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32
RCOR1 Q9UKL0 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
GRIN2B Q13224 2/20 0.31
BTK Q06187 1/20 0.31
PDE2A O00408 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
TRPV1 Q8NER1 1/20 0.30
JAK2 O60674 1/20 0.30
ROCK2 O75116 1/20 0.30
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PHKG2 P15735 1/20 0.30
RPS6KB1 P23443 1/20 0.30
MARK3 P27448 1/20 0.30
PRKCI P41743 1/20 0.30
CLK2 P49760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755773 1.00 KDM1A (0.32) KDM1ARCOR1FFAR4L3MBTL1GRIN2B
SCHEMBL8537682 1.00 KDM1A (0.32) KDM1ARCOR1FFAR4L3MBTL1GRIN2B
SCHEMBL7756512 0.94 SCN9A (0.34) KDM1ARCOR1FFAR4L3MBTL1GRIN2B
SCHEMBL7756504 0.94 SCN9A (0.34) KDM1ARCOR1FFAR4L3MBTL1GRIN2B
SCHEMBL8440999 0.94 KDM1A (0.34) KDM1ARCOR1FFAR4L3MBTL1GRIN2B
SCHEMBL8440997 0.94 KDM1A (0.34) KDM1ARCOR1FFAR4L3MBTL1GRIN2B
SCHEMBL8019223 0.91 KDM1A (0.32) KDM1ARCOR1L3MBTL1GRIN2BBTK
SCHEMBL8019221 0.91 KDM1A (0.32) KDM1ARCOR1L3MBTL1GRIN2BBTK
SCHEMBL9008569 0.91 KDM1A (0.32) KDM1ARCOR1L3MBTL1GRIN2BBTK
SCHEMBL8019225 0.91 KDM1A (0.32) KDM1ARCOR1L3MBTL1GRIN2BBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
EP-0718387-A1 A liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-26 EP disclosed