Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oxyquinoline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 known ✓ | P45452 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CCR1 | P32246 | 3/20 | 0.58 |
| ▸ | CCR5 | P51681 | 3/20 | 0.58 |
| ▸ | CCR8 | P51685 | 3/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL460412 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL296880 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL3357860 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL23175212 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL543361 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL23091400 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL2873348 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL8537748 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL22660883 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 | |
| Oxyquinoline SCHEMBL61235 | 0.95 | KDM4E (0.58) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022163546-A1 | OPTICAL THIN FILM LAMINATE AND METHOD FOR PRODUCING SAME | ＡＧＣ株式会社 | 2022-08-04 | — | — | WO | disclosed |
| EP-2995595-B1 | TRANSLUCENT SUBSTRATE, ORGANIC LED ELEMENT AND METHOD OF MANUFACTURING TRANSLUCENT SUBSTRATE | AGC INC (JP) | 2020-11-25 | — | — | EP | disclosed |
| CN-110651791-A | Application of calcium quinolate in preventing and treating plant diseases and composition thereof | 嘉兴市世诚贸易有限公司 | 2020-01-07 | — | — | CN | disclosed |
| EP-2773164-B1 | LAMINATED SUBSTRATE FOR ORGANIC LED ELEMENT, AND ORGANIC LED ELEMENT | AGC INC (JP) | 2019-10-02 | — | — | EP | disclosed |
| EP-2489643-B1 | ORGANIC LED ELEMENT UTILIZING A GLASS FOR DIFFUSION LAYER | AGC INC (JP) | 2019-01-09 | — | — | EP | disclosed |
| US-10128457-B2 | Light-emitting device and power-generating device | AGC Inc. (JP) | 2018-11-13 | — | — | US | disclosed |
| US-20170186990-A1 | LIGHT-EMITTING DEVICE AND POWER-GENERATING DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-06-29 | — | — | US | disclosed |
| EP-2999311-A1 | ORGANIC LED ELEMENT AND METHOD FOR PRODUCING ORGANIC LED ELEMENT | Asahi Glass Company, Limited (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2995595-A1 | LIGHT-TRANSMITTING SUBSTRATE, ORGANIC LED ELEMENT, AND METHOD FOR PRODUCING LIGHT-TRANSMITTING SUBSTRATE | Asahi Glass Company, Limited (JP) | 2016-03-16 | — | — | EP | disclosed |
| US-20160072093-A1 | ORGANIC LED ELEMENT, METHOD OF MANUFACTURING ORGANIC LED ELEMENT | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-03-10 | — | — | US | disclosed |
| US-8525403-B2 | Organic LED element, glass frit for diffusion layer for use in organic LED element, and method for production of diffusion layer for use in organic LED element | ASAHI GLASS COMPANY, LIMITED (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20130187141-A1 | ORGANIC EL ELEMENT, TRANSLUCENT SUBSTRATE AND METHOD OF MANUFACTURING ORGANIC EL ELEMENT | ASAHI GLASS COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| EP-2600693-A1 | GLASS FOR SCATTERING LAYER OF ORGANIC LED ELEMENT, AND ORGANIC LED ELEMENT | Asahi Glass Company, Limited (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20130134407-A1 | GLASS FOR SCATTERING LAYER OF ORGANIC LED ELEMENT, AND ORGANIC LED ELEMENT | ASAHI GLASS COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| EP-2489643-A1 | GLASS FOR DIFFUSION LAYER IN ORGANIC LED ELEMENT, AND ORGANIC LED ELEMENT UTILIZING SAME | Asahi Glass Company, Limited (JP) | 2012-08-22 | — | — | EP | disclosed |
| EP-2490506-A1 | ORGANIC LED ELEMENT, GLASS FRIT FOR DIFFUSION LAYER FOR USE IN ORGANIC LED ELEMENT, AND METHOD FOR PRODUCTION OF DIFFUSION LAYER FOR USE IN ORGANIC LED ELEMENT | Asahi Glass Company, Limited (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-20120194065-A1 | ORGANIC LED ELEMENT, GLASS FRIT FOR DIFFUSION LAYER FOR USE IN ORGANIC LED ELEMENT, AND METHOD FOR PRODUCTION OF DIFFUSION LAYER FOR USE IN ORGANIC LED ELEMENT | ASAHI GLASS COMPANY, LIMITED | 2012-08-02 | — | — | US | disclosed |
| US-20120194064-A1 | GLASS FOR DIFFUSION LAYER IN ORGANIC LED ELEMENT, AND ORGANIC LED ELEMENT UTILIZING SAME | ASAHI GLASS COMPANY, LIMITED | 2012-08-02 | — | — | US | disclosed |
| EP-2278852-A1 | SUBSTRATE FOR ELECTRONIC DEVICE, LAYERED BODY FOR ORGANIC LED ELEMENT, METHOD FOR MANUFACTURING THE SAME, ORGANIC LED ELEMENT, AND METHOD FOR MANUFACTURING THE SAME | Asahi Glass Company, Limited (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20110001159-A1 | SUBSTRATE FOR ELECTRONIC DEVICE, LAYERED BODY FOR ORGANIC LED ELEMENT, METHOD FOR MANUFACTURING THE SAME, ORGANIC LED ELEMENT, AND METHOD FOR MANUFACTURING THE SAME | ASAHI GLASS COMPANY, LIMITED | 2011-01-06 | — | — | US | disclosed |