SCHEMBL8537813

SCHEMBL8537813

CCCCCCCCCCC(=O)c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.80
TDP1 Q9NUW8 2/20 0.80
LMNA P02545 1/20 0.80
MAPT P10636 1/20 0.80
HDAC8 Q9BY41 5/20 0.71
HDAC1 Q13547 5/20 0.71
HDAC3 O15379 1/20 0.71
HDAC4 P56524 1/20 0.71
HDAC7 Q8WUI4 1/20 0.71
HDAC2 Q92769 1/20 0.71
HDAC10 Q969S8 1/20 0.71
HDAC11 Q96DB2 1/20 0.71
HDAC6 Q9UBN7 1/20 0.71
HDAC9 Q9UKV0 1/20 0.71
HDAC5 Q9UQL6 1/20 0.71
HSD17B3 P37058 6/20 0.70
CES2 O00748 2/20 0.68
CES1 P23141 2/20 0.68
NPC1 O15118 1/20 0.58
CASP3 P42574 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7889913 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL5434100 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL2125312 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL1195162 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL964590 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL967963 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL962848 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL962630 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL22528986 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8
SCHEMBL5439959 1.00 L3MBTL1 (0.80) L3MBTL1TDP1LMNAMAPTHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2869840-A1 HYDROGEL VACCINE FORMULATIONS Sigmoid Pharma Limited (IE) 2015-05-13 EP disclosed
WO-2014006215-A1 HYDROGEL VACCINE FORMULATIONS SIGMOID PHARMA LIMITED (IE) 2014-01-09 WO disclosed
EP-0856007-A1 CYCLOPEPTIDE DERIVATIVES MERCK PATENT GmbH (DE) 1998-08-05 EP disclosed
WO-1997014716-A1 CYCLOPEPTIDE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1997-04-24 WO disclosed