Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45363 | 0.90 | ALDH1A1 (0.39) | ALDH1A1LMNACYP3A4HSD17B10NPC1 | |
| SCHEMBL4318400 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP3A4HSD17B10NPC1MEN1 | |
| SCHEMBL8364755 | 0.81 | ACE2 (0.44) | PTPN11TSHRRARBTP53 | |
| Aminobenzoic Acid SCHEMBL8537849 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNACYP3A4HSD17B10PTPN11 | |
| SCHEMBL774609 | 0.78 | PPARA (0.39) | ALDH1A1MEN1POLBKMT2ARXRA | |
| SCHEMBL17995599 | 0.75 | PTPN11 (0.48) | ALDH1A1PTPN11TSHRRARBTP53 | |
| SCHEMBL18040357 | 0.74 | PTPN11 (0.47) | ALDH1A1PTPN11TSHRRARBTP53 | |
| SCHEMBL2807990 | 0.74 | PDE5A (0.47) | ALDH1A1RARB | |
| SCHEMBL128528 | 0.74 | HTT (0.46) | ALDH1A1LMNATSHRRARB | |
| SCHEMBL30522481 | 0.73 | POLB (0.45) | ALDH1A1LMNAMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919751-A | ADDITIONAL BENEFIT, OTHER THAN MERELY SOFTENING OR PERFUMING THE FABRIC. WATER INSOLUBLE OIL CATIONIC QUATERNARY AMMONIUM COMPOUND, SULPHONATE, PHOSPHATE OR COMPOUND HAVING A MOLECULAR WEIGHT GREATER THAN 1000 | LEVER BROTHERS COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0912673-A1 | FABRIC CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997044424-A1 | FABRIC CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 1997-11-27 | — | — | WO | disclosed |