SCHEMBL8537860

SCHEMBL8537860

C=C(C)C(=O)OC12CC3CC(CC(C3)C1)C2.CCCCC=C(C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CD81 P60033 1/20 0.34
TSHR P16473 2/20 0.33
EPHX2 P34913 2/20 0.32
FAAH O00519 1/20 0.32
EP300 Q09472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8534848 0.88 CD81 (0.36) CD81
SCHEMBL8533098 0.87 CYP19A1 (0.32) CD81TSHR
SCHEMBL5893934 0.86 EPHX2 (0.37) EPHX2FAAH
SCHEMBL8536939 0.82 NAAA (0.33)
Methacrylic Acid SCHEMBL21924974 0.81 CYP19A1 (0.36) EPHX2
Methacrylic Acid SCHEMBL13504160 0.80 NAAA (0.37) EPHX2
SCHEMBL45476 0.78 NAAA (0.40) EPHX2
SCHEMBL30385819 0.78 NAAA (0.32)
SCHEMBL1821534 0.77 CYP19A1 (0.35) TSHREPHX2FAAH
SCHEMBL8885416 0.77 CYP17A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975327-B2 Controlling morphology of block copolymers DOW CORNING CORPORATION (US) 2015-03-10 US disclosed
EP-2643413-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS Dow Corning Corporation (US) 2013-10-02 EP disclosed
US-20130231438-A1 Controlling Morphology of Block Copolymers DOW CORNING CORPORATION (US) 2013-09-05 US disclosed
WO-2012071330-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS DOW CORNING CORPORATION (US) 2012-05-31 WO disclosed