Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14069484 | 0.83 | CYP19A1 (0.50) | CYP19A1ALPGALPITDP1PLAA | |
| SCHEMBL4554609 | 0.83 | CYP19A1 (0.50) | CYP19A1ALPGALPITDP1PLAA | |
| SCHEMBL10247505 | 0.79 | CYP19A1 (0.72) | CYP19A1ALPGALPITDP1PLAA | |
| Hydrochloric Acid SCHEMBL412748 | 0.78 | CYP19A1 (0.70) | CYP19A1ALPGALPITDP1PLAA | |
| SCHEMBL11022381 | 0.78 | CYP19A1 (0.54) | CYP19A1ALPGALPITDP1PLAA | |
| SCHEMBL2454118 | 0.77 | CA12 (0.60) | CYP19A1ALPGALPITDP1PLAA | |
| Hydrochloric Acid SCHEMBL9996121 | 0.75 | CA12 (0.59) | CYP19A1ALPGALPITDP1PLAA | |
| SCHEMBL10879315 | 0.75 | CA12 (0.62) | CYP19A1ALPGALPITDP1PLAA | |
| SCHEMBL15991043 | 0.75 | MAOB (0.41) | L3MBTL1 | |
| SCHEMBL6799214 | 0.74 | ALPG (0.62) | CYP19A1ALPGALPITDP1PLAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683156-B1 | Acylated aminoalkanimidazoles and -triazoles | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5622982-A | ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS | SANDOZ LTD. (CH) | 1997-04-22 | — | — | US | disclosed |
| EP-0683156-A1 | Acylated aminoalkanimidazoles and -triazoles | SANDOZ LTD. (CH) | 1995-11-22 | — | — | EP | disclosed |