Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 2/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334167 | 0.83 | CES2 (0.52) | L3MBTL1ALDH1A1 | |
| SCHEMBL1509735 | 0.79 | CYP19A1 (0.71) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL23516693 | 0.78 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL4554609 | 0.78 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL14069484 | 0.78 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL8537952 | 0.78 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| Hydrochloric Acid SCHEMBL410578 | 0.78 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL10476950 | 0.75 | ALPG (0.58) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL11228752 | 0.74 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL29669830 | 0.74 | CA12 (0.56) | CYP19A1CYP11B1CYP11B2ALPGALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149115-A2 | Derivatives of 2-(1-imidazolyl)-ethanol | BOEHRINGER INGELHEIM KG (DE) | 1985-07-24 | — | — | EP | disclosed |