Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545600 | 0.88 | EEF2K (0.46) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL9259625 | 0.86 | EEF2K (0.44) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8544253 | 0.82 | ERBB2 (0.54) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8539788 | 0.76 | EEF2K (0.47) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8544169 | 0.76 | EEF2K (0.47) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8539727 | 0.75 | EEF2K (0.49) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8544637 | 0.75 | EEF2K (0.46) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL9251015 | 0.75 | EEF2K (0.46) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8539647 | 0.75 | EEF2K (0.46) | EEF2KSRCEGFRSIRT1ERBB2 | |
| SCHEMBL8538430 | 0.75 | EEF2K (0.46) | EEF2KSRCEGFRSIRT1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580502-B1 | 3-(Hydroxybenzylidenyl)-indoline-2-ones and pharmaceutical compositions containing them | ADIR (FR) | 1998-09-02 | — | — | EP | disclosed |
| US-5382593-A | Antioxidants or anticoagulants | ADIR ET COMPAGNIE (FR) | 1995-01-17 | — | — | US | disclosed |
| EP-0580502-A1 | 3-(Hydroxybenzylidenyl)-indoline-2-ones and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |