Flazasulfuron

Flazasulfuron

SCHEMBL8538148

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)(F)F)n1.COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(F)(F)F)n1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
CDK1 P06493 1/20 0.43
MAPT P10636 2/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
CYP1A2 P05177 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
SLC22A12 Q96S37 1/20 0.40
NFE2L2 Q16236 3/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flazasulfuron SCHEMBL29367690 1.00 GAA (0.56) GAACDK1MAPTTP53GLA
Flazasulfuron SCHEMBL54678 1.00 GAA (0.56) GAACDK1MAPTTP53GLA
Flazasulfuron SCHEMBL19463658 0.92 GAA (0.48) GAACDK1MAPTTP53GLA
Flazasulfuron SCHEMBL19463988 0.89 GAA (0.46) GAACDK1MAPTTP53GLA
SCHEMBL9627750 0.88 GAA (0.42) GAAMAPTALDH1A1TSHRSLC22A12
Flazasulfuron SCHEMBL19463618 0.87 GAA (0.44) GAACDK1MAPTTP53GLA
Trifloxysulfuron SCHEMBL15449154 0.86 GAA (0.55) GAACDK1MAPTTP53GLA
SCHEMBL7760051 0.86 GAA (0.41) GAACDK1SLC22A12NFE2L2
Trifloxysulfuron SCHEMBL64184 0.86 GAA (0.55) GAACDK1MAPTTP53GLA
Flazasulfuron SCHEMBL19463587 0.85 GAA (0.42) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed