Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 6/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.36 |
| ▸ | GRM6 | O15303 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifloxysulfuron SCHEMBL19464014 | 0.90 | GAA (0.43) | GAAGRM8GRM4GRM6MAPT | |
| Rimsulfuron SCHEMBL9938830 | 0.87 | GAA (0.41) | GAAGRM8GRM4GRM6MAPT | |
| Nicosulfuron SCHEMBL19463673 | 0.85 | CDK1 (0.46) | GAAGRM8GRM4GRM6MAPT | |
| Flazasulfuron SCHEMBL54678 | 0.85 | GAA (0.56) | GAAMAPTTP53GLACDK1 | |
| Flazasulfuron SCHEMBL29367690 | 0.85 | GAA (0.56) | GAAMAPTTP53GLACDK1 | |
| Flazasulfuron SCHEMBL8538148 | 0.85 | GAA (0.56) | GAAMAPTTP53GLACDK1 | |
| Flazasulfuron SCHEMBL19463618 | 0.82 | GAA (0.44) | GAAMAPTTP53GLACDK1 | |
| Flazasulfuron SCHEMBL19463658 | 0.78 | GAA (0.48) | GAAMAPTTP53GLACDK1 | |
| Rimsulfuron SCHEMBL7577414 | 0.76 | GRM8 (0.32) | GAAGRM8GRM4GRM6 | |
| Flazasulfuron SCHEMBL19463988 | 0.75 | GAA (0.46) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442962-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | Syngenta Participations AG (CH) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178582-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-19 | — | — | WO | disclosed |