SCHEMBL8538156

SCHEMBL8538156

Cc1cccc(NC(=O)NC2N=C(c3ccccc3F)c3ccccc3N(CCNC(=O)c3cccnc3)C2=O)c1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 10/20 0.61
CCKAR P32238 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8537742 0.85 CCKBR (0.68) CCKBRCCKAR
SCHEMBL9058333 0.85 CCKBR (0.68) CCKBRCCKAR
SCHEMBL8775389 0.82 CCKBR (0.51) CCKBRCCKAR
SCHEMBL8775396 0.82 CCKBR (0.51) CCKBRCCKAR
SCHEMBL8774345 0.81 CCKBR (0.82) CCKBRCCKAR
SCHEMBL8534720 0.81 CCKBR (0.82) CCKBRCCKAR
SCHEMBL8534742 0.80 CCKBR (0.69) CCKBRCCKAR
SCHEMBL8775098 0.80 CCKBR (0.69) CCKBRCCKAR
SCHEMBL9057111 0.80 CCKBR (0.71) CCKBRCCKAR
SCHEMBL8538375 0.80 CCKBR (0.71) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763437-A Benzodiazepine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-06-09 US disclosed