Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538210 | 0.89 | SLC9A1 (0.44) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL8543032 | 0.86 | SLC9A1 (0.33) | SLC9A1 | |
| SCHEMBL8536954 | 0.85 | SLC9A1 (0.49) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL6719348 | 0.84 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL8537830 | 0.83 | SLC9A1 (0.43) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL6938917 | 0.80 | SLC9A1 (0.75) | SLC9A1 | |
| SCHEMBL8538459 | 0.80 | AKR1C3 (0.33) | — | |
| SCHEMBL8538227 | 0.79 | PDGFRB (0.36) | — | |
| SCHEMBL8542373 | 0.78 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL27371046 | 0.78 | SLC9A1 (0.47) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071743-C | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 2001-09-26 | — | — | CN | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| CN-1148590-A | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 1997-04-30 | — | — | CN | disclosed |