Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CREB1 | P16220 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959798 | 0.82 | SMN1; SMN2 (0.40) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL8945665 | 0.78 | NQO1 (0.58) | SMN1; SMN2L3MBTL1ALDH1A1MEN1TP53 | |
| SCHEMBL6966209 | 0.78 | FFAR4 (0.40) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL8535881 | 0.78 | ABCB1 (0.45) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL8535928 | 0.77 | PDCD1 (0.34) | ALDH1A1KMT2A | |
| SCHEMBL7377011 | 0.74 | SMN1; SMN2 (0.40) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL7374063 | 0.74 | SMN1; SMN2 (0.40) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL7372334 | 0.74 | SMN1; SMN2 (0.40) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL8536188 | 0.73 | HDAC4 (0.41) | ABCB1SMN1; SMN2L3MBTL1POLBMAPT | |
| SCHEMBL7373050 | 0.73 | SMN1; SMN2 (0.39) | ABCB1SMN1; SMN2L3MBTL1POLBCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |